Our Bio-Manufacturing Facility

Helia’s Bio-Manufacturing Plant

Established in June 2014, our bio-manufacturing plant is located in the National High-tech Industrial Development Zone of Dezhou (Yucheng), Shandong. Recognized as a “specialized, refined, unique, and innovative” enterprise in Shandong Province, we specialize in the production of high-quality biological preservatives.

On January 12, 2023, Bota Biosciences acquired a controlling stake in Weiri (Shandong) Biotechnology Co., Ltd. through equity transfer and capital increase. This strategic partnership has brought significant enhancements to our operations:

  1. A seasoned management team with extensive experience in leading pharmaceutical companies has been appointed to elevate our management practices.
  2. Leveraging Bota’s core team of expert scientists from prominent U.S. synthetic biology companies, we are focusing on:
    • Increasing production capacity
    • Enhancing product quality
    • Diversifying our product range
    • Expanding our presence in international markets

Industry 4.0 with WeiSmart™ Smart Manufacturing

WeiSmart™ is our fully self-developed advanced smart manufacturing system designed to optimize fermentation processes in the production of natural food preservatives. It integrates real-time monitoring, data analytics, and automated controls to enhance efficiency, consistency, and cost-effectiveness, driving smarter and more sustainable production.
  • Quality Improvement: Real-time monitoring and analysis of key production data ensure the consistency and stability of the product.
  • Efficiency Optimization: Improve production efficiency and reduce human errors through automated and standardized processes, combined with big data analysis
  • Traceability: Comprehensive data recording and data analysis enable precise tracking of the entire production process, supporting continuous improvement.
  • Cost Reduction: Intelligent decision-making optimizes resource allocation and process flows and reduces production costs.
  • Intelligent Decision-Making: AI models and decision support systems analyze production data in real-time, providing optimization suggestions and automatic adjustments.
Process Workflow Management

WeiSmart™ offers real-time tracking and process management, guaranteeing the smooth progress of batch according to the procedure. With the digital production workflow, manager can easily understand the progress, adjust plans, and optimize resource allocation promptly.

Batch Workflow
Process Control Management

Parameter monitoring and control in the production process offers a balance between the real process and standardized process. The system identifies deviations through real-time data collection and analysis, ensuring consistency and stability of the product.

Real-time changes of pH over time
Comparison between batches at the same step
Equipment Management

The system offers the full lifecycle management of equipment, including procurement, warehousing, use, maintenance, and scrapping. Each step we can check the equipment effectively. It can also predict equipment failures, arrange preventive maintenance, reduce unexpected downtime, and enhance equipment utilization.

Equipment List

Our commitment to quality and safety is reflected in our international certifications:

  • ISO 9001:2015 Quality Management System
  • ISO 22000:2018 Food Safety Management System
  • Halal Certification
  • Kosher Certification